International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10)-WHO Version for ;2019-covid-expanded

Chapter IV
Endocrine, nutritional and metabolic diseases
(E00-E90)

Disorders of other endocrine glands
(E20-E35)

Excl.:
galactorrhoea (N64.3)
gynaecomastia (N62)

E20 Hypoparathyroidism

Excl.:
Di George syndrome (D82.1)
postprocedural hypoparathyroidism (E89.2)
tetany NOS (R29.0)
transitory neonatal hypoparathyroidism (P71.4)
E20.0 Idiopathic hypoparathyroidism
E20.1 Pseudohypoparathyroidism
E20.8 Other hypoparathyroidism
E20.9 Hypoparathyroidism, unspecified
Incl.:
Parathyroid tetany

E21 Hyperparathyroidism and other disorders of parathyroid gland

Excl.:
osteomalacia:
E21.0 Primary hyperparathyroidism
Incl.:
Hyperplasia of parathyroid
Osteitis fibrosa cystica generalisata [von Recklinghausen disease of bone]
E21.1 Secondary hyperparathyroidism, not elsewhere classified
Excl.:
secondary hyperparathyroidism of renal origin (N25.8)
E21.2 Other hyperparathyroidism
Incl.:
Tertiary hyperparathryoidism
Excl.:
familial hypocalciuric hypercalcaemia (E83.5)
E21.3 Hyperparathyroidism, unspecified
E21.4 Other specified disorders of parathyroid gland
E21.5 Disorder of parathyroid gland, unspecified

E22 Hyperfunction of pituitary gland

Excl.:
Cushing syndrome (E24.-)
Nelson syndrome (E24.1)
overproduction of:
  • ACTH not associated with Cushing disease (E27.0)
  • pituitary ACTH (E24.0)
  • thyroid-stimulating hormone (E05.8)
E22.0 Acromegaly and pituitary gigantism
Incl.:
Arthropathy associated with acromegaly† (M14.5*)
Overproduction of growth hormone
Excl.:
constitutional:
increased secretion from endocrine pancreas of growth hormone-releasing hormone (E16.8)
E22.1 Hyperprolactinaemia
Coding-Hint
Use additional external cause code (Chapter XX), if desired, to identify drug, if drug-induced.
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
E22.8 Other hyperfunction of pituitary gland
Incl.:
Central precocious puberty
E22.9 Hyperfunction of pituitary gland, unspecified

E23 Hypofunction and other disorders of pituitary gland

Incl.:
the listed conditions whether the disorder is in the pituitary or the hypothalamus
Excl.:
postprocedural hypopituitarism (E89.3)
E23.0 Hypopituitarism
Incl.:
Fertile eunuch syndrome
Hypogonadotropic hypogonadism
Idiopathic growth hormone deficiency
Isolated deficiency of:
  • gonadotropin
  • growth hormone
  • pituitary hormone
Kallmann syndrome
Lorain-Levi short stature
Necrosis of pituitary gland (postpartum)
Panhypopituitarism
Pituitary:
  • cachexia
  • insufficiency NOS
  • short stature
Sheehan syndrome
Simmonds disease
E23.1 Drug-induced hypopituitarism
Coding-Hint
Use additional external cause code (Chapter XX), if desired, to identify drug.
E23.2 Diabetes insipidus
Excl.:
nephrogenic diabetes insipidus (N25.1)
E23.3 Hypothalamic dysfunction, not elsewhere classified
Excl.:
Prader-Willi syndrome (Q87.1)
Russell-Silver syndrome (Q87.1)
E23.6 Other disorders of pituitary gland
Incl.:
Abscess of pituitary
Adiposogenital dystrophy
E23.7 Disorder of pituitary gland, unspecified

E24 Cushing syndrome

E24.0 Pituitary-dependent Cushing disease
Incl.:
Overproduction of pituitary ACTH
Pituitary-dependent hyperadrenocorticism
E24.1 Nelson syndrome
E24.2 Drug-induced Cushing syndrome
Coding-Hint
Use additional external cause code (Chapter XX), if desired, to identify drug.
E24.3 Ectopic ACTH syndrome
E24.4 Alcohol-induced pseudo-Cushing syndrome
E24.8 Other Cushing syndrome
E24.9 Cushing syndrome, unspecified

E25 Adrenogenital disorders

Incl.:
adrenogenital syndromes, virilizing or feminizing, whether acquired or due to adrenal hyperplasia consequent on inborn enzyme defects in hormone synthesis
female:
  • adrenal pseudohermaphroditism
  • heterosexual precocious pseudopuberty
male:
  • isosexual precocious pseudopuberty
  • macrogenitosomia praecox
  • sexual precocity with adrenal hyperplasia
virilization (female)
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
Incl.:
Congenital adrenal hyperplasia
21-Hydroxylase deficiency
Salt-losing congenital adrenal hyperplasia
E25.8 Other adrenogenital disorders
Incl.:
Idiopathic adrenogenital disorder
Coding-Hint
Use additional external cause code (Chapter XX), if desired, to identify drug, if drug-induced.
E25.9 Adrenogenital disorder, unspecified
Incl.:
Adrenogenital syndrome NOS

E26 Hyperaldosteronism

E26.0 Primary hyperaldosteronism
Incl.:
Conn syndrome
Primary aldosteronism due to adrenal hyperplasia (bilateral)
E26.1 Secondary hyperaldosteronism
E26.8 Other hyperaldosteronism
Incl.:
Bartter syndrome
E26.9 Hyperaldosteronism, unspecified

E27 Other disorders of adrenal gland

E27.0 Other adrenocortical overactivity
Incl.:
Overproduction of ACTH, not associated with Cushing disease
Premature adrenarche
Excl.:
Cushing syndrome (E24.-)
E27.1 Primary adrenocortical insufficiency
Incl.:
Addison disease
Autoimmune adrenalitis
Excl.:
amyloidosis (E85.-)
tuberculous Addison disease (A18.7)
Waterhouse-Friderichsen syndrome (A39.1)
E27.2 Addisonian crisis
Incl.:
Adrenal crisis
Adrenocortical crisis
E27.3 Drug-induced adrenocortical insufficiency
Coding-Hint
Use additional external cause code (Chapter XX), if desired, to identify drug.
E27.4 Other and unspecified adrenocortical insufficiency
Incl.:
Adrenal:
  • haemorrhage
  • infarction
Adrenocortical insufficiency NOS
Hypoaldosteronism
Excl.:
adrenoleukodystrophy [Addison-Schilder] (E71.3)
Waterhouse-Friderichsen syndrome (A39.1)
E27.5 Adrenomedullary hyperfunction
Incl.:
Adrenomedullary hyperplasia
Catecholamine hypersecretion
E27.8 Other specified disorders of adrenal gland
Incl.:
Abnormality of cortisol-binding globulin
E27.9 Disorder of adrenal gland, unspecified

E28 Ovarian dysfunction

Excl.:
isolated gonadotropin deficiency (E23.0)
postprocedural ovarian failure (E89.4)
E28.0 Estrogen excess
Coding-Hint
Use additional external cause code (Chapter XX), if desired, to identify drug, if drug-induced.
E28.1 Androgen excess
Incl.:
Hypersecretion of ovarian androgens
Coding-Hint
Use additional external cause code (Chapter XX), if desired, to identify drug, if drug-induced.
E28.2 Polycystic ovarian syndrome
Incl.:
Sclerocystic ovary syndrome
Stein-Leventhal syndrome
E28.3 Primary ovarian failure
Incl.:
Decreased estrogen
Premature menopause NOS
Resistant ovary syndrome
Excl.:
menopausal and female climacteric states (N95.1)
pure gonadal dysgenesis (Q99.1)
Turner syndrome (Q96.-)
E28.8 Other ovarian dysfunction
Incl.:
Ovarian hyperfunction NOS
E28.9 Ovarian dysfunction, unspecified

E29 Testicular dysfunction

Excl.:
androgen resistance syndrome (E34.5)
azoospermia or oligospermia NOS (N46)
isolated gonadotropin deficiency (E23.0)
Klinefelter syndrome (Q98.0-Q98.2, Q98.4)
postprocedural testicular hypofunction (E89.5)
testicular feminization (syndrome) (E34.5)
E29.0 Testicular hyperfunction
Incl.:
Hypersecretion of testicular hormones
E29.1 Testicular hypofunction
Incl.:
5-Alpha-reductase deficiency (with male pseudohermaphroditism)
Defective biosynthesis of testicular androgen NOS
Testicular hypogonadism NOS
Coding-Hint
Use additional external cause code (Chapter XX), if desired, to identify drug, if drug-induced.
E29.8 Other testicular dysfunction
E29.9 Testicular dysfunction, unspecified

E30 Disorders of puberty, not elsewhere classified

E30.0 Delayed puberty
Incl.:
Constitutional delay of puberty
Delayed sexual development
E30.1 Precocious puberty
Incl.:
Precocious menstruation
Excl.:
Albright(-McCune)(-Sternberg) syndrome (Q78.1)
central precocious puberty (E22.8)
congenital adrenal hyperplasia (E25.0)
female heterosexual precocious pseudopuberty (E25.-)
male isosexual precocious pseudopuberty (E25.-)
E30.8 Other disorders of puberty
Incl.:
Premature thelarche
E30.9 Disorder of puberty, unspecified

E31 Polyglandular dysfunction

Excl.:
ataxia telangiectasia [Louis-Bar] (G11.3)
dystrophia myotonica [Steinert] (G71.1)
pseudohypoparathyroidism (E20.1)
E31.0 Autoimmune polyglandular failure
Incl.:
Schmidt syndrome
E31.1 Polyglandular hyperfunction
Excl.:
multiple endocrine adenomatosis (D44.8)
E31.8 Other polyglandular dysfunction
E31.9 Polyglandular dysfunction, unspecified

E32 Diseases of thymus

Excl.:
aplasia or hypoplasia with immunodeficiency (D82.1)
myasthenia gravis (G70.0)
E32.0 Persistent hyperplasia of thymus
Incl.:
Hypertrophy of thymus
E32.1 Abscess of thymus
E32.8 Other diseases of thymus
E32.9 Disease of thymus, unspecified

E34 Other endocrine disorders

Excl.:
pseudohypoparathyroidism (E20.1)
E34.0 Carcinoid syndrome
Note:

May be used as an additional code, if desired, to identify functional activity associated with a carcinoid tumour.

E34.1 Other hypersecretion of intestinal hormones
E34.2 Ectopic hormone secretion, not elsewhere classified
E34.3 Short stature, not elsewhere classified
Incl.:
Short stature:
  • NOS
  • constitutional
  • Laron-type
  • psychosocial
Excl.:
progeria (E34.8)
Russell-Silver syndrome (Q87.1)
short-limbed stature with immunodeficiency (D82.2)
short stature:
  • achondroplastic (Q77.4)
  • hypochondroplastic (Q77.4)
  • in specific dysmorphic syndromes - code to syndrome - see Alphabetical Index
  • nutritional (E45)
  • pituitary (E23.0)
  • renal (N25.0)
E34.4 Constitutional tall stature
Incl.:
Constitutional gigantism
E34.5 Androgen resistance syndrome
Incl.:
Male pseudohermaphroditism with androgen resistance
Peripheral hormonal receptor disorder
Reifenstein syndrome
Testicular feminization (syndrome)
E34.8 Other specified endocrine disorders
Incl.:
Pineal gland dysfunction
Progeria
E34.9 Endocrine disorder, unspecified
Incl.:
Disturbance:
  • endocrine NOS
  • hormone NOS

E35* Disorders of endocrine glands in diseases classified elsewhere

E35.0* Disorders of thyroid gland in diseases classified elsewhere
Incl.:
Tuberculosis of thyroid gland (A18.8†)
E35.1* Disorders of adrenal glands in diseases classified elsewhere
Incl.:
Tuberculous Addison disease (A18.7†)
Waterhouse-Friderichsen syndrome (meningococcal) (A39.1†)
E35.8* Disorders of other endocrine glands in diseases classified elsewhere